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Where Can I Buy Vegetable Glycerin And Propylene Glycol

Introduction: Electronic nicotine delivery systems (ENDS) vary on a wide range of characteristics that may affect reinforcement value and use. One characteristic is the ratio of two solvents commonly used in most e-liquids: propylene glycol (PG) and vegetable glycerin (VG). The goal of this study was to understand how PG/VG ratio affects subjective effects, reinforcement value, and tobacco use patterns among current smokers who try using ENDS.

where can i buy vegetable glycerin and propylene glycol

Electronic nicotine delivery systems, or e-cigarettes, utilize a liquid solution that normally contains propylene glycol (PG) and vegetable glycerin (VG) to generate vapor and act as a carrier for nicotine and flavorings. Evidence indicated these "carriers" reduced growth and survival of epithelial cells including those of the airway. We hypothesized that 3% PG or PG mixed with VG (3% PG/VG, 55:45) inhibited glucose uptake in human airway epithelial cells as a first step to reducing airway cell survival. Exposure of H441 or human bronchiolar epithelial cells (HBECs) to PG and PG/VG (30-60 min) inhibited glucose uptake and mitochondrial ATP synthesis. PG/VG inhibited glycolysis. PG/VG and mannitol reduced cell volume and height of air-liquid interface cultures. Mannitol, but not PG/VG, increased phosphorylation of p38 MAPK. PG/VG reduced transepithelial electrical resistance, which was associated with increased transepithelial solute permeability. PG/VG decreased fluorescence recovery after photobleaching of green fluorescent protein-linked glucose transporters GLUT1 and GLUT10, indicating that glucose transport function was compromised. Puffing PG/VG vapor onto the apical surface of primary HBECs for 10 min to mimic the effect of e-cigarette smoking also reduced glucose transport. In conclusion, short-term exposure to PG/VG, key components of e-cigarettes, decreased glucose transport and metabolism in airway cells. We propose that this was a result of PG/VG reduced cell volume and membrane fluidity, with further consequences on epithelial barrier function. Taking these results together, we suggest these factors contribute to reduced defensive properties of the epithelium. We propose that repeated/chronic exposure to these agents are likely to contribute to airway damage in e-cigarette users.

The team of researchers, in the pilot clinical trial have found that those who smoked e-cigarettes twice a day for just a month had higher levels of chemicals such as propylene glycol in their blood. This was associated with inflammatory changes in their lungs. The count of the inflammatory cells in their lungs rises over time, speculate the researchers. However, they agree that this was a small study of a short duration and the magnitude of the changes noted in the lungs were small.

Mandal, Ananya. (2019, October 18). Vaping propylene glycol and vegetable glycerine may lead to lung inflammation. News-Medical. Retrieved on March 31, 2023 from

Mandal, Ananya. "Vaping propylene glycol and vegetable glycerine may lead to lung inflammation". News-Medical. (accessed March 31, 2023).

Mandal, Ananya. 2019. Vaping propylene glycol and vegetable glycerine may lead to lung inflammation. News-Medical, viewed 31 March 2023,

The most common side effects of using e-liquid containing propylene glycol are symptoms of dehydration, like dry mouth, sore throat, and increased thirst. It is advised to drink more water and liquids than usual for the first few weeks of using your e-cigarette. If hydrated properly, these symptoms usually last anywhere from a few days to a week as the body gets used to the propylene glycol. Be aware that any unusual reactions could be side effects from quitting smoking, and not necessarily because of the PG.

It is important to note that the risk of being allergic to vegetable glycerin is very low, making it a useful alternative for people who have issues when vaping e-juice containing PG. If you are allergic to palm oil or coconut oil then VG could prove a problem, but this is relatively uncommon. Diabetics could possibly experience problems with metabolizing VG, but this would not be an issue at the levels used in vaping.

Vaping refers to inhaling a vapor created from electronic cigarettes (e-cigarettes) or other vaping devices. E-cigarettes are battery-powered smoking devices. They have cartridges that are filled with liquid that usually contain nicotine, chemicals, and flavorings. The liquid is heated into a vapor to be inhaled, hence the name of the practice. One of the many chemicals that vape cartridges often contain is vegetable glycerin. Our drug rehabilitation center is sharing vaping vegetable glycerin side effects and dangers.

Researchers have recently found that vegetable glycerin can lead to inflammation of the lungs due to long-term vaping or e-cigarette use. One study on the dangers of vaping glycerin ran for four weeks, during which 34 were randomized to using flavor- and nicotine-free e-cigs or to a control group of no-use. At the end of the study, researchers discovered that the side effects of inhaling vegetable glycerin included inflammation in the lungs. The study also found that those who smoked e-cigarettes twice a day for a month contained higher levels of chemicals like propylene glycol in their blood.1

E-liquids contain four ingredients: a PG or VG base, nicotine, water and flavorings. The base, or carrier, holds the nicotine and flavor in suspension so your e-cigarette can produce those nice clouds of smoke-like vapor. Both propylene glycol and vegetable glycerin are non-toxic organic compounds and generally considered safe for consumption. In fact, they are widely used as food additives in a variety of commercially available products.

@hyulien partly right as propylene glycol is more similar to mineral oil and petrol derived, and glycerine is organic( meaning carbon based) in production, they are both actually organic in nature and vg is actually not oil based but a sugar alcohol that leads to the production of triglycerides (lipids) but not an oil itself. I believe pg is oil based but could be alcohol, I forget and have to revisit past research. Both are considered safe by consumption but who has really studied the effects of smoking it?

Propylene glycol is not in anti freeze so do not get the confused with ethylene glycol. However propylene glycol CAN cause allergic reactions in sensitive people who smoke the pg e cigs. I also suffered with headaches, nausea and dizziness. I opted for 100% VG and my symptoms have now vanished much to my relief!

I definitely recommend switching to a different flavor for a while, as menthol can cause this kind of side effects. If possible, stop vaping completely for a few days, and see if the congestion goes away, or at least switch to 100% VG for a while, to eliminate the possibility of an allergy to propylene glycol

the e-juice consists of VG veggie glysarine and PG propylene glycol the PG gives a throat hit like you would get with a normal smoke it depends on the person weather they want 50/50 vg and pg or 70.30 of eather or strait vg or pg vg is more vapor and pg is as i said the throat hit pg is used in radiator coolent and this is what ppl are carrying on about pg as vg are both food grade items and used in many diffrent foods the fact they use it in coolent is neather here or there sadly most of the world are left brained they see this as bad but its not think about it if jelly dident freeze they could use that it wouldent make the jelly bad for humans same with pg. it can also contain destilled water and flavoring witch is food or alcahole what ever flavors you want to use in it.

Propylene glycol is safe. Propylene ethanol is what is used to make antifreeze and such. I buy my liquid either 50/50 or 80VG/20PG. I have had no issues. Just drink plenty of water or juice for the first few weeks and maybe use a saline nasal spray and all should be fine. Most of the time the bad side effects comes from the nicotine extracted in China. Make sure who you buy from is willing to reveal where their nicotine comes from. I smoked a pack and a 1/2 a day and when I started vaping I stop smoking within 3 days. Have not smoked since. ? Cigarettes are far more dangerous than anything in eliquid (excluding nicotine that comes from China)

Propylene glycol is used to dilute liquid nicotine for e-liquid. It is a colorless, odorless substance and does not alter the flavor of e-liquid.Vegetable glycerin is a derivative of palm oil and is plant-based.

My information came from the MSDS sheets for Glycerine, which there are many but here are a couple; _Vegetable_Glycerine_USP.pdf food grade vegetable Glycerine, non food grade vegetable glycerine. Note how similar the two are. -c1.pdf A public health statement on Acrolein.

Because bulk glycerin is readily available and cheap, its uses are countless. In fact, many of the products that you find on our website are very high in glycerol content. Here at Plant Guru Inc, we only use the highest quality pure vegetable USP glycerin which is one thing that makes us stand out from some of our competition. Some of our competitors use the waste byproduct from local bio diesel manufacturers, which is common, but also very dangerous. Without proper preparation, it is possible for lower grade glycerin to have unwanted additives that are undesirable for personal care products. Because of this, we highly recommend that if you are going to manufacture your own product you only use a very high grade USP or food grade bulk glycerin from a reputable supplier.

Propylene glycol is a clear and nearly odorless substance as well, and has a somewhat gelatinous consistency. One of its most important properties is that it absorbs water. This ingredient is utilized in many different ways for food industry and pharmaceutical purposes. The Food and Drug Administration (FDA) has deemed propylene glycol, a manufactured liquid ingredient, as generally safe to use in food. 041b061a72


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